See Roche Biochemical Pathways - A legacy in scientific education . I used to work at the University of Cambridge Computer Laboratory, where it was my job to maintain the software on people's personal computers. In order to stay sane I spent most of my spare time at the gym or cycling. I used to have an A2 printout of this poster on my wall. I loved it because it was presented as a kind of circuit. You could imagine simulating cellular metabolism on a computer by modelling reaction rates, concentrations etc. in π-calculus and plotting the physical evolution of the system in terms of some series of, what? Graphs of concentrations, temperatures, and reaction-rates? But they would have to be spatially represented somehow, ... how would you do that? How would you know what these processes you had modelled were actually doing physically? When you think about it this way, you actually find that you are asking yourself "How did they produce this abstraction?" What materials did...