Professor Peter Elwood - Aspirin and cancer: the emerging evidence

He started by looking for the worlds expert on Salicylic acid in plants (6:50). If you search for the prefix "salicyl" you get 69 references in Brian Goodwin's Handbook of biotransformations of aromatic compounds. Many of them are in metabolic pathways of micro-organisms so we should expect them to be active compounds in the gut of animals. See Anton Petrov - Mindblowing Discoveries About Bacteria Living Inside of Our Guts. 

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Today, before I saw this video, we were pulling up Willow shoots on Stanmore Common. I made this video last night:

See On Plants and Human Consciousness and https://www.monicagagliano.com/

See also Terence Tao and Richard Feynman.

For some models of putative mechanisms of morphogenetics in plants see Dynamics of the Goodwin-Trainor mechanochemical model Acta Biotheoretica 42: 137-146, 1994. and references therein

• Goodwin, B.C. and L.E.H. Trainor (1985). Tip and whorl morphogenesis in Acetabularia by calcium-regulated strain fields. J. theor. Biol. 117: 79-106.
• Trainor, L.E.H. and B.C. Goodwin (1986). Stability analysis on a set of calcium-regulated viscoelastic equations. Physica 21D: 137-145
• Briere, C. and B.C. Goodwin (1988). Geometry and dynamics of tip morphogenesis in Acetabularia J. theor. Biol. 131: 461-475.
• Briere, C. and B.C. Goodwin (1990). Effects of calcium input/output on the stability of a system for calcium regulated viscoelastic strain fields. J. Math. Biol. 28: 585-593.
  

Simulations have shown that there are regions of the parameter space where the solutions of the Goodwin-Trainor model are not asymptotically stable but can be periodic or aperiodic. Whether such kinds of solutions correspond to a biologically plausible behaviour of the calcium-cytogel system remains of course to be demonstrated. A first argument would be the numerous experimental evidence showing the complexity of the dynamic of calcium in the cytoplasm. Oscillations of the cytosolic calcium in a variety of animal cells are well known. More complex phenomena, such as travelling waves and spiral patterns have also been observed (Lechleiter et al, 1991).

See also The Goodwin Oscillator and its Legacy Acta Biotheoretica 69, pages857–874 (2021).:

In the 1960’s Brian Goodwin published a couple of mathematical models showing how feedback inhibition can lead to oscillations and discussed possible implications of this behaviour for the physiology of the cell. He also presented key ideas about the rich dynamics that may result from the coupling between such biochemical oscillators. Goodwin’s work motivated a series of theoretical investigations aiming at identifying minimal mechanisms to generate limit cycle oscillations and deciphering design principles of biological oscillators. The three-variable Goodwin model (adapted by Griffith) can be seen as a core model for a large class of biological systems, ranging from ultradian to circadian clocks. We summarize here main ideas and results brought by Goodwin and review a couple of modeling works directly or indirectly inspired by Goodwin’s findings.